ClinVar Miner

Submissions for variant CYP2C19*3 (rs4986893)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Clinical Pharmacogenetics Implementation Consortium RCV000783656 SCV000922179 drug response CYP2C19: no function practice guideline curation
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics RCV000291495 SCV000331713 other not provided 2015-12-28 criteria provided, single submitter clinical testing
OMIM RCV000018397 SCV000038679 drug response Mephenytoin, poor metabolism of 2009-06-01 no assertion criteria provided literature only
OMIM RCV000018398 SCV000038680 drug response Proguanil, poor metabolism of 2009-06-01 no assertion criteria provided literature only
PharmGKB RCV000211151 SCV000268362 drug response clopidogrel response - Efficacy, Toxicity/ADR 2017-01-12 reviewed by expert panel curation PharmGKB Level of Evidence 1A: Annotation for a variant-drug combination in a CPIC or medical society-endorsed PGx guideline, or implemented at a PGRN site or in another major health system.

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