ClinVar Miner

Submissions for variant NM_000038.5(APC):c.5274T>A (p.Ser1758=) (rs199600387)

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Total submissions: 8
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000131241 SCV000186198 benign Hereditary cancer-predisposing syndrome 2014-10-01 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Co-occurence with a mutation in another gene that clearly explains a proband's phenotype
Color RCV000131241 SCV000681726 likely benign Hereditary cancer-predisposing syndrome 2016-06-13 criteria provided, single submitter clinical testing
Counsyl RCV000198344 SCV000488414 likely benign Familial adenomatous polyposis 1 2016-03-22 criteria provided, single submitter clinical testing
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000502224 SCV000591189 benign not specified criteria provided, single submitter clinical testing
Invitae RCV000198344 SCV000252930 likely benign Familial adenomatous polyposis 1 2018-01-05 criteria provided, single submitter clinical testing
PreventionGenetics RCV000679064 SCV000805428 likely benign not provided 2017-01-12 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000502224 SCV000600112 benign not specified 2017-06-19 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000679064 SCV000887535 benign not provided 2017-06-19 criteria provided, single submitter clinical testing

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