ClinVar Miner

Submissions for variant NM_000038.6(APC):c.1158A>C (p.Ala386=)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color Diagnostics, LLC DBA Color Health RCV003585900 SCV004361831 likely benign Hereditary cancer-predisposing syndrome 2020-03-26 criteria provided, single submitter clinical testing
Labcorp Genetics (formerly Invitae), Labcorp RCV004371485 SCV004389152 likely benign Familial adenomatous polyposis 1 2024-01-19 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV004371485 SCV004933018 benign Familial adenomatous polyposis 1 2024-03-01 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.

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