ClinVar Miner

Submissions for variant NM_000038.6(APC):c.1350G>C (p.Val450=)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV004565539 SCV004319471 likely benign Familial adenomatous polyposis 1 2023-08-31 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV004565539 SCV004932542 benign Familial adenomatous polyposis 1 2024-03-01 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.

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