ClinVar Miner

Submissions for variant NM_000038.6(APC):c.1488A>G (p.Thr496=)

dbSNP: rs9282599
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color Diagnostics, LLC DBA Color Health RCV001804578 SCV002053332 likely benign Hereditary cancer-predisposing syndrome 2021-06-14 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV004564719 SCV004933074 benign Familial adenomatous polyposis 1 2024-03-01 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.

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