ClinVar Miner

Submissions for variant NM_000038.6(APC):c.2508A>C (p.Ser836=)

dbSNP: rs1580623312
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV004563599 SCV001631969 likely benign Familial adenomatous polyposis 1 2022-10-17 criteria provided, single submitter clinical testing
All of Us Research Program, National Institutes of Health RCV004004377 SCV004819098 likely benign Classic or attenuated familial adenomatous polyposis 2023-01-10 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV004563599 SCV004932719 benign Familial adenomatous polyposis 1 2024-03-14 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.

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