ClinVar Miner

Submissions for variant NM_000038.6(APC):c.2860T>C (p.Leu954=) (rs863224278)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000196948 SCV000252915 likely benign Familial adenomatous polyposis 1 2017-03-31 criteria provided, single submitter clinical testing
Ambry Genetics RCV000566184 SCV000672503 likely benign Hereditary cancer-predisposing syndrome 2015-12-18 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Synonymous alterations with insufficient evidence to classify as benign,In silico models in agreement (benign)
Integrated Genetics/Laboratory Corporation of America RCV000589111 SCV000694019 likely benign not specified 2019-08-20 criteria provided, single submitter clinical testing
Color RCV000566184 SCV000909256 likely benign Hereditary cancer-predisposing syndrome 2018-11-01 criteria provided, single submitter clinical testing

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