ClinVar Miner

Submissions for variant NM_000038.6(APC):c.2958T>C (p.Tyr986=) (rs746581330)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000475346 SCV000562587 likely benign Familial adenomatous polyposis 1 2017-05-15 criteria provided, single submitter clinical testing
Ambry Genetics RCV000567624 SCV000667374 likely benign Hereditary cancer-predisposing syndrome 2015-09-05 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Synonymous alterations with insufficient evidence to classify as benign,In silico models in agreement (benign)
Color RCV000567624 SCV000681565 likely benign Hereditary cancer-predisposing syndrome 2016-09-15 criteria provided, single submitter clinical testing
CeGaT Praxis fuer Humangenetik Tuebingen RCV000585539 SCV000693183 uncertain significance not provided 2017-10-31 criteria provided, single submitter clinical testing

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