ClinVar Miner

Submissions for variant NM_000038.6(APC):c.3264G>A (p.Lys1088=) (rs114774495)

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Total submissions: 9
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000211908 SCV000167005 benign not specified 2014-03-10 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Ambry Genetics RCV000129142 SCV000183863 benign Hereditary cancer-predisposing syndrome 2015-07-16 criteria provided, single submitter clinical testing
Invitae RCV000200836 SCV000252582 benign Familial adenomatous polyposis 1 2018-01-11 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000211908 SCV000600079 benign not specified 2017-02-13 criteria provided, single submitter clinical testing
Color RCV000129142 SCV000681588 benign Hereditary cancer-predisposing syndrome 2016-04-19 criteria provided, single submitter clinical testing
Integrated Genetics/Laboratory Corporation of America RCV000586811 SCV000694029 benign not provided 2016-03-14 criteria provided, single submitter clinical testing
PreventionGenetics,PreventionGenetics RCV000211908 SCV000805392 benign not specified 2016-07-20 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000586811 SCV000887520 benign not provided 2017-02-13 criteria provided, single submitter clinical testing
Mayo Clinic Genetic Testing Laboratories,Mayo Clinic RCV000211908 SCV000691733 likely benign not specified no assertion criteria provided clinical testing

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