ClinVar Miner

Submissions for variant NM_000038.6(APC):c.3624C>T (p.Thr1208=) (rs730882125)

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Total submissions: 7
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000679057 SCV000211906 likely benign not provided 2019-02-22 criteria provided, single submitter clinical testing
Ambry Genetics RCV000163381 SCV000213921 likely benign Hereditary cancer-predisposing syndrome 2014-06-18 criteria provided, single submitter clinical testing
GeneDx RCV000440935 SCV000512071 likely benign not specified 2017-04-04 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000440935 SCV000591149 likely benign not specified 2015-05-14 criteria provided, single submitter clinical testing
Color RCV000163381 SCV000681618 likely benign Hereditary cancer-predisposing syndrome 2016-11-22 criteria provided, single submitter clinical testing
PreventionGenetics,PreventionGenetics RCV000679057 SCV000805400 likely benign not provided 2016-11-22 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000679057 SCV001133326 benign not provided 2019-06-06 criteria provided, single submitter clinical testing

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