ClinVar Miner

Submissions for variant NM_000038.6(APC):c.422+10C>G

dbSNP: rs899376835
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV002150930 SCV002467245 likely benign Familial adenomatous polyposis 1 2022-04-18 criteria provided, single submitter clinical testing
Fulgent Genetics, Fulgent Genetics RCV002500307 SCV002806705 likely benign Desmoid disease, hereditary; Familial adenomatous polyposis 1; Hepatocellular carcinoma; Gastric cancer; Colorectal cancer; Gastric adenocarcinoma and proximal polyposis of the stomach 2021-11-24 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV002150930 SCV004931434 likely benign Familial adenomatous polyposis 1 2024-02-23 criteria provided, single submitter clinical testing This variant is considered likely benign. This variant is intronic and is not expected to impact mRNA splicing.

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