ClinVar Miner

Submissions for variant NM_000038.6(APC):c.423-16A>T (rs78919815)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color RCV000579652 SCV000681658 benign Hereditary cancer-predisposing syndrome 2016-03-18 criteria provided, single submitter clinical testing
GeneDx RCV000123675 SCV000167018 benign not specified 2014-04-04 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Mayo Clinic Genetic Testing Laboratories,Mayo Clinic RCV000123675 SCV000691703 benign not specified no assertion criteria provided clinical testing
Systems Biology Platform Zhejiang California International NanoSystems Institute RCV000073900 SCV000105493 cancer Familial colorectal cancer no assertion criteria provided not provided Converted during submission to other.

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