ClinVar Miner

Submissions for variant NM_000038.6(APC):c.5715A>G (p.Gln1905=) (rs779869418)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000165369 SCV000216096 likely benign Hereditary cancer-predisposing syndrome 2014-08-08 criteria provided, single submitter clinical testing
Invitae RCV000203946 SCV000261129 likely benign Familial adenomatous polyposis 1 2015-10-12 criteria provided, single submitter clinical testing
GeneDx RCV000444858 SCV000532189 likely benign not specified 2016-09-22 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Color RCV000165369 SCV000911738 likely benign Hereditary cancer-predisposing syndrome 2017-11-26 criteria provided, single submitter clinical testing

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