Total submissions: 5
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Gene |
RCV000432139 | SCV000523758 | likely benign | not specified | 2016-01-26 | criteria provided, single submitter | clinical testing | This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease. |
Invitae | RCV000469890 | SCV000562598 | likely benign | Familial adenomatous polyposis 1 | 2016-11-08 | criteria provided, single submitter | clinical testing | |
Ambry Genetics | RCV000566862 | SCV000672555 | likely benign | Hereditary cancer-predisposing syndrome | 2017-01-06 | criteria provided, single submitter | clinical testing | Lines of evidence used in support of classification: Synonymous alterations with insufficient evidence to classify as benign |
Color | RCV000566862 | SCV000904169 | likely benign | Hereditary cancer-predisposing syndrome | 2018-08-07 | criteria provided, single submitter | clinical testing | |
Mayo Clinic Genetic Testing Laboratories, |
RCV000432139 | SCV000691759 | likely benign | not specified | no assertion criteria provided | clinical testing |