ClinVar Miner

Submissions for variant NM_000038.6(APC):c.7818A>C (p.Val2606=)

dbSNP: rs1221514715
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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV004571014 SCV001668081 likely benign Familial adenomatous polyposis 1 2023-04-06 criteria provided, single submitter clinical testing
Color Diagnostics, LLC DBA Color Health RCV003584956 SCV004357736 likely benign Hereditary cancer-predisposing syndrome 2021-10-27 criteria provided, single submitter clinical testing
All of Us Research Program, National Institutes of Health RCV004007092 SCV004835722 likely benign Classic or attenuated familial adenomatous polyposis 2023-07-07 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV004571014 SCV005082036 benign Familial adenomatous polyposis 1 2024-04-11 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.

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