ClinVar Miner

Submissions for variant NM_000038.6(APC):c.867C>G (p.Ala289=)

dbSNP: rs2149762899
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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
All of Us Research Program, National Institutes of Health RCV004007942 SCV004821625 likely benign Classic or attenuated familial adenomatous polyposis 2023-02-15 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV004371937 SCV004932472 benign Familial adenomatous polyposis 1 2024-02-27 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.
Labcorp Genetics (formerly Invitae), Labcorp RCV004371937 SCV005791562 likely benign Familial adenomatous polyposis 1 2024-02-15 criteria provided, single submitter clinical testing

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