ClinVar Miner

Submissions for variant NM_000051.4(ATM):c.3577-15T>C

dbSNP: rs1057521733
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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000440010 SCV000524374 likely benign not specified 2016-02-08 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Color Diagnostics, LLC DBA Color Health RCV000579529 SCV000682144 likely benign Hereditary cancer-predisposing syndrome 2017-06-02 criteria provided, single submitter clinical testing
Labcorp Genetics (formerly Invitae), Labcorp RCV003500531 SCV004331319 likely benign Ataxia-telangiectasia syndrome 2023-05-20 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV004591203 SCV005085655 likely benign Familial cancer of breast 2024-05-15 criteria provided, single submitter clinical testing This variant is considered likely benign. This variant is intronic and is not expected to impact mRNA splicing.

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