ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.1438T>C (p.Cys480Arg) (rs397507267)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000164042 SCV000214648 uncertain significance Hereditary cancer-predisposing syndrome 2014-07-18 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Insufficient or conflicting evidence,In silico models in agreement (benign)
Sharing Clinical Reports Project (SCRP) RCV000031321 SCV000053926 uncertain significance Breast-ovarian cancer, familial 2 2009-05-29 no assertion criteria provided clinical testing

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