ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.1627C>A (p.His543Asn) (rs80358446)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000510047 SCV000607756 uncertain significance Hereditary cancer-predisposing syndrome 2017-05-08 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Insufficient or Conflicting Evidence
Breast Cancer Information Core (BIC) (BRCA2) RCV000077259 SCV000145899 uncertain significance Breast-ovarian cancer, familial 2 2002-05-29 no assertion criteria provided clinical testing
Color RCV000510047 SCV000688715 uncertain significance Hereditary cancer-predisposing syndrome 2018-09-29 criteria provided, single submitter clinical testing
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000504335 SCV000591757 likely benign not specified 2012-04-05 criteria provided, single submitter clinical testing
Sharing Clinical Reports Project (SCRP) RCV000077259 SCV000109056 uncertain significance Breast-ovarian cancer, familial 2 2013-05-21 no assertion criteria provided clinical testing

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