ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.1951G>T (p.Asp651Tyr) (rs80358482)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000132142 SCV000187213 likely benign Hereditary cancer-predisposing syndrome 2017-07-03 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Other strong data supporting benign classification
Breast Cancer Information Core (BIC) (BRCA2) RCV000112998 SCV000145983 uncertain significance Breast-ovarian cancer, familial 2 no assertion criteria provided clinical testing
Counsyl RCV000112998 SCV000488019 uncertain significance Breast-ovarian cancer, familial 2 2015-12-16 criteria provided, single submitter clinical testing

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