ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.235A>G (p.Ile79Val) (rs80358502)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000561580 SCV000668684 likely benign Hereditary cancer-predisposing syndrome 2016-07-20 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: In silico models in agreement (benign),Other data supporting benign classification
Breast Cancer Information Core (BIC) (BRCA2) RCV000031364 SCV000146419 uncertain significance Breast-ovarian cancer, familial 2 2004-02-20 no assertion criteria provided clinical testing
Color RCV000561580 SCV000911860 uncertain significance Hereditary cancer-predisposing syndrome 2018-05-18 criteria provided, single submitter clinical testing
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000500366 SCV000591666 uncertain significance not specified 2015-11-20 criteria provided, single submitter clinical testing
Sharing Clinical Reports Project (SCRP) RCV000031364 SCV000053969 uncertain significance Breast-ovarian cancer, familial 2 2008-01-31 no assertion criteria provided clinical testing

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