ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.2926T>A (p.Ser976Thr) (rs144862123)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000562818 SCV000661148 likely benign Hereditary cancer-predisposing syndrome 2017-06-02 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: In silico models in agreement (benign),Subpopulation frequency in support of benign classification
Color RCV000562818 SCV000903061 benign Hereditary cancer-predisposing syndrome 2015-09-23 criteria provided, single submitter clinical testing
Genetic Services Laboratory, University of Chicago RCV000503409 SCV000593709 likely benign not specified 2017-02-07 criteria provided, single submitter clinical testing
Genome Diagnostics Laboratory,University Medical Center Utrecht RCV000624981 SCV000743279 likely benign Breast-ovarian cancer, familial 2 2017-07-28 criteria provided, single submitter clinical testing

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