ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.4110C>A (p.Gly1370=) (rs758430181)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000551821 SCV000635336 likely benign Hereditary breast and ovarian cancer syndrome 2019-12-31 criteria provided, single submitter clinical testing
Integrated Genetics/Laboratory Corporation of America RCV000586666 SCV000694736 likely benign not specified 2019-08-21 criteria provided, single submitter clinical testing
Counsyl RCV000663033 SCV000786069 likely benign Breast-ovarian cancer, familial 2 2018-02-15 criteria provided, single submitter clinical testing
Ambry Genetics RCV001021892 SCV001183563 likely benign Hereditary cancer-predisposing syndrome 2019-11-14 criteria provided, single submitter clinical testing In silico models in agreement (benign);Synonymous alterations with insufficient evidence to classify as benign
Color RCV001021892 SCV001358892 likely benign Hereditary cancer-predisposing syndrome 2020-01-02 criteria provided, single submitter clinical testing

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