ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.4681C>A (p.His1561Asn) (rs2219594)

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Total submissions: 15
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
A.C.Camargo Cancer Center / LGBM, A.C.Camargo Cancer Center RCV000414161 SCV000492495 uncertain significance Neoplasm of the breast criteria provided, single submitter research
ARUP Laboratories, Molecular Genetics and Genomics,ARUP Laboratories RCV000755479 SCV000602797 benign not provided 2018-02-14 criteria provided, single submitter clinical testing
Ambry Genetics RCV000128957 SCV000172838 benign Hereditary cancer-predisposing syndrome 2014-11-19 criteria provided, single submitter clinical testing
Baylor Genetics RCV000463461 SCV000541066 benign Familial cancer of breast 2017-02-23 criteria provided, single submitter clinical testing
Breast Cancer Information Core (BIC) (BRCA2) RCV000077334 SCV000146468 uncertain significance Breast-ovarian cancer, familial 2 2002-05-29 no assertion criteria provided clinical testing
Color RCV000128957 SCV000683643 likely benign Hereditary cancer-predisposing syndrome 2015-03-12 criteria provided, single submitter clinical testing
Counsyl RCV000077334 SCV000154088 benign Breast-ovarian cancer, familial 2 2014-03-18 criteria provided, single submitter literature only
DNA and Cytogenetics Diagnostics Unit,Erasmus Medical Center RCV000077334 SCV000744460 likely benign Breast-ovarian cancer, familial 2 2015-09-21 criteria provided, single submitter clinical testing
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics RCV000120328 SCV000225182 benign not specified 2014-08-04 criteria provided, single submitter clinical testing
ITMI RCV000120328 SCV000084480 not provided not specified 2013-09-19 no assertion provided reference population
Integrated Genetics/Laboratory Corporation of America RCV000044469 SCV000494327 benign Hereditary breast and ovarian cancer syndrome 2014-03-28 criteria provided, single submitter clinical testing
Invitae RCV000044469 SCV000072482 benign Hereditary breast and ovarian cancer syndrome 2018-01-12 criteria provided, single submitter clinical testing
Michigan Medical Genetics Laboratories,University of Michigan RCV000077334 SCV000267769 benign Breast-ovarian cancer, familial 2 2016-04-21 criteria provided, single submitter clinical testing
PreventionGenetics RCV000120328 SCV000805712 benign not specified 2017-03-20 criteria provided, single submitter clinical testing
Sharing Clinical Reports Project (SCRP) RCV000077334 SCV000109131 benign Breast-ovarian cancer, familial 2 2012-05-01 no assertion criteria provided clinical testing

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