ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.4926T>C (p.Asn1642=) (rs1057520859)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000444543 SCV000518721 likely benign not specified 2015-10-20 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV000462283 SCV000560430 likely benign not provided 2019-02-16 criteria provided, single submitter clinical testing
Color RCV000581202 SCV000688907 likely benign Hereditary cancer-predisposing syndrome 2017-08-09 criteria provided, single submitter clinical testing

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