ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.6826C>A (p.Pro2276Thr) (rs80358907)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000569837 SCV000665989 uncertain significance Hereditary cancer-predisposing syndrome 2016-01-06 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Insufficient or conflicting evidence,In silico models in agreement (benign)
Breast Cancer Information Core (BIC) (BRCA2) RCV000113653 SCV000146946 uncertain significance Breast-ovarian cancer, familial 2 2010-09-18 no assertion criteria provided clinical testing

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