ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.709G>A (p.Asp237Asn) (rs398122575)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000562449 SCV000665933 uncertain significance Hereditary cancer-predisposing syndrome 2017-11-27 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Rarity in general population databases (dbsnp, esp, 1000 genomes),Insufficient evidence
Counsyl RCV000076987 SCV000489623 uncertain significance Breast-ovarian cancer, familial 2 2016-10-31 criteria provided, single submitter clinical testing
Mendelics RCV000709294 SCV000838744 uncertain significance Hereditary breast and ovarian cancer syndrome 2018-07-02 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000076987 SCV000296494 uncertain significance Breast-ovarian cancer, familial 2 2016-06-08 criteria provided, single submitter clinical testing
Sharing Clinical Reports Project (SCRP) RCV000076987 SCV000108784 uncertain significance Breast-ovarian cancer, familial 2 2009-03-17 no assertion criteria provided clinical testing

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