ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.7193C>G (p.Thr2398Ser) (rs80358947)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000166255 SCV000217035 uncertain significance Hereditary cancer-predisposing syndrome 2014-10-07 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Insufficient or conflicting evidence,In silico models in agreement (benign)
Color RCV000166255 SCV000906932 uncertain significance Hereditary cancer-predisposing syndrome 2018-06-20 criteria provided, single submitter clinical testing
Breast Cancer Information Core (BIC) (BRCA2) RCV000113718 SCV000147036 uncertain significance Breast-ovarian cancer, familial 2 no assertion criteria provided clinical testing

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