ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.740T>C (p.Ile247Thr) (rs80358962)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000045201 SCV000073214 likely benign not provided 2019-01-08 criteria provided, single submitter clinical testing
Ambry Genetics RCV000220097 SCV000274049 uncertain significance Hereditary cancer-predisposing syndrome 2016-02-29 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Insufficient or conflicting evidence,In silico models in agreement (benign)
Counsyl RCV000114112 SCV000489054 uncertain significance Breast-ovarian cancer, familial 2 2016-08-10 criteria provided, single submitter clinical testing
Breast Cancer Information Core (BIC) (BRCA2) RCV000114112 SCV000147643 uncertain significance Breast-ovarian cancer, familial 2 2002-05-29 no assertion criteria provided clinical testing

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