ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.7733G>A (p.Gly2578Glu) (rs398122590)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000217106 SCV000277907 uncertain significance Hereditary cancer-predisposing syndrome 2015-08-21 criteria provided, single submitter clinical testing
Invitae RCV000122931 SCV000166189 uncertain significance Hereditary breast and ovarian cancer syndrome 2014-06-11 no assertion criteria provided clinical testing The interpretation for this sequence variant was made by Invitae based on the ACMG guidelines.
Sharing Clinical Reports Project (SCRP) RCV000077008 SCV000108805 uncertain significance Breast-ovarian cancer, familial 2 2008-04-14 no assertion criteria provided clinical testing

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