ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.7977-14G>A (rs879255467)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color RCV000579778 SCV000683925 likely benign Hereditary cancer-predisposing syndrome 2017-03-13 criteria provided, single submitter clinical testing
DNA and Cytogenetics Diagnostics Unit,Erasmus Medical Center RCV000624986 SCV000744529 benign Breast-ovarian cancer, familial 2 2015-09-21 criteria provided, single submitter clinical testing
GeneDx RCV000609403 SCV000714507 likely benign not specified 2017-06-13 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Genome Diagnostics Laboratory,University Medical Center Utrecht RCV000624986 SCV000743339 likely benign Breast-ovarian cancer, familial 2 2015-05-11 criteria provided, single submitter clinical testing
Invitae RCV000460238 SCV000560466 benign Hereditary breast and ovarian cancer syndrome 2017-06-08 criteria provided, single submitter clinical testing

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