ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.7977-15T>G (rs431825361)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Color RCV000776347 SCV000911710 likely benign Hereditary cancer-predisposing syndrome 2015-10-30 criteria provided, single submitter clinical testing
Counsyl RCV000082984 SCV000488495 uncertain significance Breast-ovarian cancer, familial 2 2016-04-13 criteria provided, single submitter clinical testing
GeneDx RCV000435845 SCV000512389 likely benign not specified 2016-01-08 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Invitae RCV000227332 SCV000283328 likely benign Hereditary breast and ovarian cancer syndrome 2017-12-29 criteria provided, single submitter clinical testing
Sharing Clinical Reports Project (SCRP) RCV000082984 SCV000115058 uncertain significance Breast-ovarian cancer, familial 2 2012-03-12 no assertion criteria provided clinical testing

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