ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.8462T>C (p.Ile2821Thr) (rs80359096)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000502475 SCV000592194 uncertain significance not specified 2013-01-30 criteria provided, single submitter clinical testing
Ambry Genetics RCV000575289 SCV000668632 uncertain significance Hereditary cancer-predisposing syndrome 2016-03-25 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: Insufficient or conflicting evidence
Breast Cancer Information Core (BIC) (BRCA2) RCV000113938 SCV000147370 uncertain significance Breast-ovarian cancer, familial 2 no assertion criteria provided clinical testing

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