ClinVar Miner

Submissions for variant NM_000059.3(BRCA2):c.9274del (p.Tyr3092fs) (rs397507424)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Evidence-based Network for the Interpretation of Germline Mutant Alleles (ENIGMA) RCV000031809 SCV000301369 pathogenic Breast-ovarian cancer, familial 2 2016-09-08 reviewed by expert panel curation Variant allele predicted to encode a truncated non-functional protein.
Genologica Medica RCV000031809 SCV000577976 pathogenic Breast-ovarian cancer, familial 2 2017-01-01 criteria provided, single submitter clinical testing
Sharing Clinical Reports Project (SCRP) RCV000031809 SCV000054417 pathogenic Breast-ovarian cancer, familial 2 2008-08-18 no assertion criteria provided clinical testing

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