Submissions for variant NM_000059.4(BRCA2):c.426-37T>A

gnomAD frequency: 0.00005  dbSNP: rs81002859

Total submissions: 7

Submitter	RCV	SCV	Clinical significance	Condition	Last evaluated	Review status	Method	Comment
Labcorp Genetics (formerly Invitae), Labcorp	RCV000044382	SCV000072395	benign	Hereditary breast ovarian cancer syndrome	2022-11-24	criteria provided, single submitter	clinical testing
Department of Pathology and Laboratory Medicine, Sinai Health System	RCV000501629	SCV000591681	likely benign	not specified		criteria provided, single submitter	clinical testing
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories	RCV000501629	SCV000602809	benign	not specified	2016-10-13	criteria provided, single submitter	clinical testing
Sema4, Sema4	RCV002255270	SCV002533862	likely benign	Hereditary cancer-predisposing syndrome	2021-02-01	criteria provided, single submitter	curation
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital	RCV000501629	SCV004242638	likely benign	not specified	2024-02-06	criteria provided, single submitter	clinical testing
CeGaT Center for Human Genetics Tuebingen	RCV004546424	SCV005042477	likely benign	not provided	2024-04-01	criteria provided, single submitter	clinical testing	BRCA2: BP4
Breast Cancer Information Core (BIC) (BRCA2)	RCV000113568	SCV000146819	uncertain significance	Breast-ovarian cancer, familial, susceptibility to, 2	1997-11-13	no assertion criteria provided	clinical testing