ClinVar Miner

Submissions for variant NM_000059.4(BRCA2):c.631+25C>T

gnomAD frequency: 0.00048  dbSNP: rs367871824
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Total submissions: 10
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Michigan Medical Genetics Laboratories,University of Michigan RCV000210958 SCV000195949 benign Breast-ovarian cancer, familial, susceptibility to, 2 2014-11-03 criteria provided, single submitter clinical testing
Counsyl RCV000210958 SCV000488647 likely benign Breast-ovarian cancer, familial, susceptibility to, 2 2016-05-12 criteria provided, single submitter clinical testing
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000501701 SCV000591701 likely benign not specified criteria provided, single submitter clinical testing
Genome Diagnostics Laboratory, University Medical Center Utrecht RCV000210958 SCV000743245 likely benign Breast-ovarian cancer, familial, susceptibility to, 2 2015-05-04 criteria provided, single submitter clinical testing
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center RCV000210958 SCV000744388 benign Breast-ovarian cancer, familial, susceptibility to, 2 2015-09-21 criteria provided, single submitter clinical testing
Mendelics RCV000210958 SCV001138972 likely benign Breast-ovarian cancer, familial, susceptibility to, 2 2019-05-28 criteria provided, single submitter clinical testing
National Health Laboratory Service, Universitas Academic Hospital and University of the Free State RCV002222176 SCV002025981 likely benign Hereditary breast ovarian cancer syndrome 2021-11-16 criteria provided, single submitter clinical testing
Clinical Genetics Laboratory, Department of Pathology,Netherlands Cancer Institute RCV001689741 SCV001906385 likely benign not provided no assertion criteria provided clinical testing
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+ RCV001689741 SCV001952860 likely benign not provided no assertion criteria provided clinical testing
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital RCV000501701 SCV002550258 likely benign not specified 2021-10-05 no assertion criteria provided clinical testing

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