ClinVar Miner

Submissions for variant NM_000059.4(BRCA2):c.631+43G>T

gnomAD frequency: 0.00137  dbSNP: rs276174869
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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Michigan Medical Genetics Laboratories,University of Michigan RCV000113914 SCV000267736 benign Breast-ovarian cancer, familial, susceptibility to, 2 2016-04-21 criteria provided, single submitter clinical testing
Genome Diagnostics Laboratory, University Medical Center Utrecht RCV000113914 SCV000743246 likely benign Breast-ovarian cancer, familial, susceptibility to, 2 2014-10-09 criteria provided, single submitter clinical testing
Breast Cancer Information Core (BIC) (BRCA2) RCV000113914 SCV000147337 uncertain significance Breast-ovarian cancer, familial, susceptibility to, 2 2010-12-17 no assertion criteria provided clinical testing
Clinical Genetics Laboratory, Department of Pathology,Netherlands Cancer Institute RCV001689600 SCV001906014 likely benign not provided no assertion criteria provided clinical testing
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+ RCV001689600 SCV001953824 likely benign not provided no assertion criteria provided clinical testing
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital RCV002267813 SCV002550259 likely benign not specified 2022-01-21 no assertion criteria provided clinical testing

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