Total submissions: 12
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Evidence- |
RCV000113848 | SCV001161617 | benign | Breast-ovarian cancer, familial, susceptibility to, 2 | 2019-06-18 | reviewed by expert panel | curation | IARC class based on posterior probability from multifactorial likelihood analysis, thresholds for class as per Plon et al. 2008 (PMID: 18951446). Class 1 based on posterior probability = 2.09E-09 |
Labcorp Genetics |
RCV000045364 | SCV000073377 | benign | Hereditary breast ovarian cancer syndrome | 2023-07-17 | criteria provided, single submitter | clinical testing | |
Counsyl | RCV000113848 | SCV000220692 | likely benign | Breast-ovarian cancer, familial, susceptibility to, 2 | 2014-09-11 | criteria provided, single submitter | literature only | |
Department of Pathology and Laboratory Medicine, |
RCV000500547 | SCV000592164 | likely benign | not specified | 2017-10-25 | criteria provided, single submitter | clinical testing | |
Mendelics | RCV000113848 | SCV001139198 | likely benign | Breast-ovarian cancer, familial, susceptibility to, 2 | 2019-05-28 | criteria provided, single submitter | clinical testing | |
Center for Genomic Medicine, |
RCV000500547 | SCV002551668 | benign | not specified | 2023-08-15 | criteria provided, single submitter | clinical testing | |
Breakthrough Genomics, |
RCV001795041 | SCV005236533 | benign | not provided | criteria provided, single submitter | not provided | ||
Breast Cancer Information Core |
RCV000113848 | SCV000147234 | uncertain significance | Breast-ovarian cancer, familial, susceptibility to, 2 | 2010-12-17 | no assertion criteria provided | clinical testing | |
Genome Diagnostics Laboratory, |
RCV000500547 | SCV002034151 | benign | not specified | no assertion criteria provided | clinical testing | ||
Clinical Genetics Laboratory, |
RCV001795041 | SCV002034320 | likely benign | not provided | no assertion criteria provided | clinical testing | ||
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, |
RCV001795041 | SCV002037361 | likely benign | not provided | no assertion criteria provided | clinical testing | ||
Clinical Genetics DNA and cytogenetics Diagnostics Lab, |
RCV000500547 | SCV002038075 | benign | not specified | no assertion criteria provided | clinical testing |