ClinVar Miner

Submissions for variant NM_000075.4(CDK4):c.135T>C (p.Gly45=)

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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Myriad Genetics, Inc. RCV004787580 SCV005403916 benign Melanoma, cutaneous malignant, susceptibility to, 3 2024-09-24 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.
Labcorp Genetics (formerly Invitae), Labcorp RCV005105080 SCV005839051 likely benign Familial melanoma 2024-10-06 criteria provided, single submitter clinical testing

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