Total submissions: 3
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Gene |
RCV000603143 | SCV000732278 | likely benign | not specified | 2017-03-15 | criteria provided, single submitter | clinical testing | This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease. |
Labcorp Genetics |
RCV001481524 | SCV001685870 | likely benign | Familial melanoma | 2023-02-07 | criteria provided, single submitter | clinical testing | |
Myriad Genetics, |
RCV004788033 | SCV005407156 | benign | Melanoma, cutaneous malignant, susceptibility to, 3 | 2024-09-25 | criteria provided, single submitter | clinical testing | This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing. |