ClinVar Miner

Submissions for variant NM_000075.4(CDK4):c.444G>A (p.Val148=)

dbSNP: rs1595110484
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Total submissions: 2
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Labcorp Genetics (formerly Invitae), Labcorp RCV001435900 SCV001638731 likely benign Familial melanoma 2019-09-12 criteria provided, single submitter clinical testing
Myriad Genetics, Inc. RCV004793490 SCV005406440 benign Melanoma, cutaneous malignant, susceptibility to, 3 2024-09-25 criteria provided, single submitter clinical testing This variant is considered benign. This variant is a silent/synonymous amino acid change and it is not expected to impact splicing.

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