ClinVar Miner

Submissions for variant NM_000075.4(CDK4):c.522+8G>A (rs758294834)

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Total submissions: 5
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV001081840 SCV000252619 benign Hereditary melanoma 2020-11-21 criteria provided, single submitter clinical testing
GeneDx RCV000439686 SCV000512541 benign not specified 2015-04-24 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
PreventionGenetics,PreventionGenetics RCV000439686 SCV000805808 benign not specified 2017-06-27 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000759738 SCV000889267 benign not provided 2018-07-09 criteria provided, single submitter clinical testing
True Health Diagnostics RCV000664264 SCV000787988 likely benign Hereditary cancer-predisposing syndrome 2018-02-28 no assertion criteria provided clinical testing

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