Total submissions: 4
Submitter | RCV | SCV | Clinical significance | Condition | Last evaluated | Review status | Method | Comment |
---|---|---|---|---|---|---|---|---|
Gene |
RCV000603907 | SCV000721072 | likely benign | not specified | 2017-07-10 | criteria provided, single submitter | clinical testing | This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease. |
Labcorp Genetics |
RCV002531538 | SCV003020133 | likely benign | Familial melanoma | 2024-11-02 | criteria provided, single submitter | clinical testing | |
Laboratory of Medical Genetics Unit, |
RCV003315247 | SCV004012978 | uncertain significance | Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype | 2019-10-09 | criteria provided, single submitter | research | |
Myriad Genetics, |
RCV004788016 | SCV005403836 | likely benign | Melanoma, cutaneous malignant, susceptibility to, 3 | 2024-09-26 | criteria provided, single submitter | clinical testing | This variant is considered likely benign. This variant is intronic and is not expected to impact mRNA splicing. |