ClinVar Miner

Submissions for variant NM_000179.2(MSH6):c.2418C>T (p.Ser806=) (rs770992427)

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Total submissions: 6
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000162791 SCV000213269 likely benign Hereditary cancer-predisposing syndrome 2014-10-22 criteria provided, single submitter clinical testing
EGL Genetic Diagnostics,Eurofins Clinical Diagnostics RCV000590110 SCV000230041 uncertain significance not provided 2014-10-07 criteria provided, single submitter clinical testing
Invitae RCV001082493 SCV000253094 likely benign Hereditary nonpolyposis colorectal neoplasms 2019-12-31 criteria provided, single submitter clinical testing
GeneDx RCV000178055 SCV000513692 likely benign not specified 2017-09-07 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Integrated Genetics/Laboratory Corporation of America RCV000178055 SCV000695814 likely benign not specified 2019-09-03 criteria provided, single submitter clinical testing
Color RCV000162791 SCV000911115 likely benign Hereditary cancer-predisposing syndrome 2017-10-27 criteria provided, single submitter clinical testing

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