ClinVar Miner

Submissions for variant NM_000179.2(MSH6):c.260+10T>G (rs193922342)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories RCV000126841 SCV000604275 benign not specified 2016-09-16 criteria provided, single submitter clinical testing
Color RCV000449453 SCV000537462 likely benign Hereditary cancer-predisposing syndrome 2015-07-29 criteria provided, single submitter clinical testing
GeneDx RCV000126841 SCV000170370 benign not specified 2013-09-17 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Integrated Genetics/Laboratory Corporation of America RCV000030263 SCV000052930 likely benign Lynch syndrome 2015-10-02 no assertion criteria provided clinical testing

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