ClinVar Miner

Submissions for variant NM_000179.2(MSH6):c.2964C>A (p.Arg988=) (rs144288981)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV000205737 SCV000260274 likely benign not provided 2019-02-10 criteria provided, single submitter clinical testing
GeneDx RCV000421482 SCV000515974 likely benign not specified 2016-06-02 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Color RCV000580377 SCV000685340 likely benign Hereditary cancer-predisposing syndrome 2017-05-22 criteria provided, single submitter clinical testing
Integrated Genetics/Laboratory Corporation of America RCV000421482 SCV000919749 likely benign not specified 2019-08-29 criteria provided, single submitter clinical testing

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