ClinVar Miner

Submissions for variant NM_000179.2(MSH6):c.3024C>T (p.Thr1008=) (rs587780675)

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Total submissions: 7
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Invitae RCV001082858 SCV000166224 likely benign Hereditary nonpolyposis colorectal neoplasms 2019-12-31 criteria provided, single submitter clinical testing
Ambry Genetics RCV000162464 SCV000212826 likely benign Hereditary cancer-predisposing syndrome 2014-08-01 criteria provided, single submitter clinical testing
Color RCV000162464 SCV000537454 likely benign Hereditary cancer-predisposing syndrome 2016-06-14 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000122960 SCV000601554 likely benign not provided 2019-07-08 criteria provided, single submitter clinical testing
GeneDx RCV000507567 SCV000729045 benign not specified 2015-06-24 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Integrated Genetics/Laboratory Corporation of America RCV000507567 SCV000917773 likely benign not specified 2019-08-29 criteria provided, single submitter clinical testing
CeGaT Praxis fuer Humangenetik Tuebingen RCV000122960 SCV001152297 likely benign not provided 2017-04-01 criteria provided, single submitter clinical testing

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