ClinVar Miner

Submissions for variant NM_000179.2(MSH6):c.3079G>C (p.Val1027Leu) (rs876658397)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
Ambry Genetics RCV000216842 SCV000273550 likely benign Hereditary cancer-predisposing syndrome 2016-12-29 criteria provided, single submitter clinical testing Lines of evidence used in support of classification: In silico models in agreement (benign),Other data supporting benign classification
Invitae RCV000227272 SCV000283782 likely benign not provided 2019-02-13 criteria provided, single submitter clinical testing
Department of Pathology and Laboratory Medicine,Sinai Health System RCV000503628 SCV000592621 uncertain significance not specified 2016-06-30 criteria provided, single submitter clinical testing
Quest Diagnostics Nichols Institute San Juan Capistrano RCV000227272 SCV001134420 uncertain significance not provided 2018-08-13 criteria provided, single submitter clinical testing

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