ClinVar Miner

Submissions for variant NM_000179.2(MSH6):c.3557-40T>A (rs189436849)

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Total submissions: 4
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
International Society for Gastrointestinal Hereditary Tumours (InSiGHT) RCV000074884 SCV000108097 likely benign Lynch syndrome I 2014-10-10 reviewed by expert panel curation Meets class 2 criteria
Mendelics RCV000986735 SCV001135840 likely benign Hereditary nonpolyposis colorectal cancer type 5 2019-05-28 criteria provided, single submitter clinical testing
Mayo Clinic Genetic Testing Laboratories,Mayo Clinic RCV000201976 SCV000257264 benign not specified no assertion criteria provided research
University of Washington Department of Laboratory Medicine, University of Washington RCV000209307 SCV000265307 likely benign Hereditary cancer-predisposing syndrome 2015-12-01 no assertion criteria provided clinical testing

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