ClinVar Miner

Submissions for variant NM_000179.2(MSH6):c.4002-14T>C (rs587781041)

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Total submissions: 3
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Submitter RCV SCV Clinical significance Condition Last evaluated Review status Method Comment
GeneDx RCV000126837 SCV000170365 benign not specified 2014-03-25 criteria provided, single submitter clinical testing This variant is considered likely benign or benign based on one or more of the following criteria: it is a conservative change, it occurs at a poorly conserved position in the protein, it is predicted to be benign by multiple in silico algorithms, and/or has population frequency not consistent with disease.
Counsyl RCV000409445 SCV000488115 uncertain significance Hereditary nonpolyposis colorectal cancer type 5 2015-12-29 criteria provided, single submitter clinical testing
Color RCV000776217 SCV000911384 likely benign Hereditary cancer-predisposing syndrome 2016-01-25 criteria provided, single submitter clinical testing

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